Fellowships Funded by the
National Niemann-Pick Disease Foundation
(To see a listing of the Research Grants funded by the CCNNPDF/NNPDF, click here .)
(To see a listing of the Clinical Research and Services funded by the CCNNPDF/NNPDF, click here .)
The Canadian Chapter of the National Niemann-Pick Disease Foundation (CCNNPDF) is a sister chapter to the National Niemann-Pick Disease Foundation (NNPDF) (U.S.) and receives administrative support from the NNPDF. Money raised through the CCNNPDF is invested in Niemann-Pick Disease research through the NNPDF's research program with guidance from the NNPDF's Scientific Advisory Board (SAB), Board of Directors, and Research Committee. This partnership helps eliminate redundancy and maximizes the impact of research dollars. (Tammy Vaughan, chair of the CCNNPDF, serves as secretary of the NNPDF, and is on the NNPDF's Research Committee.)
The research funded by the NNPDF is made possible in great part due to the efforts of our NPD families in both the U.S. and Canada, and their extended support network via local community-sponsored events. The NNPDF is truly grateful for this support.
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Item # |
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Additional
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| 11 |
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10/2012 - 10/2014 |
Deepti Gadi, Ph.D.
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Understanding the cellular mechanism of HDAC inhibitors for the treatment of NPC disease | |
| 10 |
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10/2012 - 10/2014 |
Stephanie M. Cologna, Ph.D.
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Differential Protein Expression Profiling in Cerebrospinal Fluid from Niemann-Pick Disease, type C1 Patients | |
| 9 |
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10/2012 - 10/2014 |
Lluis Samaranch Gusi, Ph.D.
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AAV9-mediated human acid sphingomyelinase expression in nonhuman primate brain: Preclinical development of gene therapy for Niemann-Pick disease type A | |
| 8 |
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9/2011 -
9/2012 |
Andrew Munkacsi, Ph.D.
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Defining the molecular basis of HDAC inhibitors to treat murine, feline, and human models of NPC
$50,000 Jointly sponsored by NNPDF and CCNNPDF In progress - Possible extension |
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| 7 |
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9/2010 -
9/2013 |
Dorothea Maetzel, Ph.D.
Sponsor: Rudolf Jaenisch, M.D. (Whitehead Institute for Biomedical Research; Cambridge, Massachusetts; USA) |
In Vitro modelling of Niemann-Pick type C Disease Using Patient-Specific Induced Pluripotent Stem Cells
Received third year extension of additional $50,000
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| 6 |
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9/2010 -
9/2013 |
Nicholas Cianciola, Ph.D.
Sponsor: Cathleen Carlin, Ph.D. (School of Medicine, Case Western Reserve University; Cleveland, Ohio; USA) |
Activation of an alternative cholesterol homeostatic mechanism in NPC
Received third year extension of additional $50,000
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| 5 |
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4/2010 -
4/2012 |
Fabrizio Vacca, Ph.D.
Sponsor: Professor Jean Gruenberg (University of Geneva, Switzerland) |
Analysis of cholesterol export from purified endosomes in NPC cellular models
$100,000 Jointly sponsored by NNPDF and CCNPDF Completed |
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| 4 |
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9/2009 - 9/2011 |
Ian Williams, Ph.D.
Sponsor: Professor Fran Platt (University of Oxford, UK) |
Neurobiology of Purkinje Cells in NPC1
$100,000
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3 |
9/15/2004 - 9/14/2006 |
Nobutaka Ohgami, Ph.D.
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Demonstration of NPC1 as a lipid binding protein in Vitro
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2 |
3/15/2003 - 3/14/2005 |
Heng-Ling Liou, Ph.D.
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The Role of NPC2 (Niemann-Pick Disease Type C2) Protein in Lysosomal Cholesterol Trafficking
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1 |
3/15/2003 - 3/14/2005 |
Amit Kumar Choudhury, Ph.D.
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Reduction of Lipid Accumulation in Niemann-Pick Fibroblasts by Modulation of Membrane Trafficking
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“The Canadian Chapter of the National Niemann-Pick Disease Foundation (CCNNPDF) does not engage in the practice of medicine. It is not a medical authority nor does it claim to have medical knowledge. This site is an educational service of the Canadian Chapter of the National Niemann-Pick Disease Foundation and is not meant to provide diagnostic or treatment advice. Information contained or suggested on this Web site does not constitute medical advice. For all information related to care, medication or treatment, the CCNNPDF recommends consulting a physician to determine if information presented is applicable. Please review these additional cautions about medical information provided on the Internet.”